Endocrine Abstracts

Survival requires the ability to adapt to cycles of feast and famine, yet the underlying mechanisms to maintain metabolic balance during extremes of nutrient excess remain poorly understood. We recently discovered that the classic growth factor FGF1 is induced in white adipose tissue (WAT) in response to high-fat-diet (HFD) and repressed during fastong, pointing to an unexpected metabolic function. Thus, FGF1 participates in both fed-state and fasted-state responses. In WAT, F...